I am a traditional RPM packager and for the sake of building a better GNU/Linux audio ecosystem for everyone, I'd like to explore cross-distro packaging.
I have zero experience with AppImage and Flatpak, I have dabbled with Guix.
From what I have understood, Guix is the best for packagers in terms of tooling (since it uses a real programming language for builds, Scheme, in a declarative way), but also the hardest to use for final users, who can't simply download an installer, run it and be done with it. Another thing I don't like about Guix is that they put all packages from the same category in the same build file (example). For these reasons, even though I would prefer to cheer for a GNU project which uses a Lisp, I am afraid it isn't an option for attracting people who right now are using Mac or Windows on GNU/Linux, but it's great for FLOSS hackers!
I do not know much about AppImage and FlatPak. I rarely use them because I don't trust the most popular Flatpak repo (FlatHub), which has a lot of proprietary stuff in it, and I am not sure an equivalent to FlatHub exists for AppImage (I only found this). In any case, I'd prefer if FLOSS-only repos existed for either or both, possibly run by a trusted nonprofit organisation.
Can you tell me more about AppImage, FlatPak or Guix? Are there any audio-specific issues concerning these systems?
Thank you
PS: I am leaving out snap because I don't like the fact that their server code is nonfree, so I would not consider it cross-distro