@Impostor or anyone else using a Debian-based Distro...
Are you interested in trying the PipeWire tools from AV Linux, where you can set the quantum and sample rate per session from metadata commands. It's a Deb and should work in Mint, it will also install/require yad for the dialogs. Of course this would globally set the Q and S/R and not run 2 separate S/R's so maybe it doesn't help you..?
They are here if you want to try:
https://bandshed.net/packages/AVL-MXe-2 ... -1_all.deb
*Note this does not install or configure PipeWire if it doesn't exist on the system, it simply works with what is already installed..