The biggest problem I've encountered is getting rid of xruns when playing live eg when routing an instrument into an effects processor running in a host on the computer or when playing softsynths live. Thus far I've not been able to achieve the goal of an xrun free session testing on different hardware platforms (some of them being high-end) with different audio interfaces, some PCI, some USB.What stops you switching to Linux?
All with (different era) Intel chipset motherboards.
Audio Interfaces used:
RME HDSP 9652 PCI
Linux Mint 17 64Bit + Lowlatency kernel
Minimal testing with AVLinux + LM 17 32Bit
Testing was done mainly on 64Bit systems. Perhaps one can achieve better results with 32Bit.....