For the standalone, the file menu, Audio-midi Settings, Audio tab, choose asio, and wineasio for the driver, and in the midi tab, turn on your input and output ports. It auto-connects in the
qjackctl Audio tab. For the plugin, I use reaper, (if more plugins are to be used) and its preferences to set up the same things. (If you start the plugin with fst, you will have to manually connect
in the qjackctl Audio and midi tabs.) Thats all I do. Hope it works!

wine /home/user/.wine/drive_c/Program*Files/Native*Instruments/Absynth*5/Absynth*5.exe
fst /home/user/.wine/drive_c/Program*Files/Steinberg/VstPlugins/Absynth*5.dll